Apigenin attenuates copper-mediated β-amyloid neurotoxicity through antioxidation, mitochondrion protection and MAPK signal inactivation in an AD cell model
L Zhao, J Wang, Y Wang, X Fa - Brain research, 2013 - Elsevier
Apigenin, belonging to a less toxic and non-mutagenic flavone subclass of flavonoids, has
been reported to possess numerous biological activities beneficial to health. Although
evidence has shown apigenin might exert its protective effects by reducing the toxicity
induced by amyloid-β peptides (Aβ), the precise mechanism is unclear. In the present study,
we investigated the in vitro neuroprotective activity of apigenin interrelated with amyloid
toxicity and mental homeostasis in an Alzheimer's disease (AD) cell model and explored its …
been reported to possess numerous biological activities beneficial to health. Although
evidence has shown apigenin might exert its protective effects by reducing the toxicity
induced by amyloid-β peptides (Aβ), the precise mechanism is unclear. In the present study,
we investigated the in vitro neuroprotective activity of apigenin interrelated with amyloid
toxicity and mental homeostasis in an Alzheimer's disease (AD) cell model and explored its …
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